International Society of DAO Deficiency promotes the progress of science and industry in favour of the population affected by this metabolic disorder.

Become a member of the Society is free and it allows you to get access to scientific publications on the field of DAO Deficiency, get access to the member directory of the Society and be able to get in touch with them, and also get passes for events and activities.

To become a member of any of our three committees before you must be associated in one of the member areas of the Society and subsequently send a request for admission to one of them, it will e reviewed and granted by the Board of Directors.

The Society is composed of three Committees

Their fundamental mission is to collaborate and advice the Society`s Board of directors to ensure better delivery of its activities and work plans, allowing the generation of knowledge, innovation and health benefits.

Our committees are integrated by experts belonging to clinical, assistential and research groups, enterprises and patient associations. These represent the interaction between the worlds of science, industry and society, respectively.

We must be aware of the large percentage of the world’s population that is affected by adverse symptoms related to the effects of diet and with alterations in the functioning of the intestinal metabolism.
Migraine
1.050 million people affected by migraine
12%
Irritable Bowel Syndrome: 611 million people affected
7.1%
ADHD: 388 million people affected
2.1%
Fibromyalgia: 124 million people affected

What is DAO deficiency?

The decrease in the Diamine Oxidase enzime activity, which metabolize the histamine adquired from diet, triggers it absortion and acumulation in tissues and organs, producing many adverse symptons in the organism:

 

symptoms dao deficiency
Have an optimal activity of the enzyme diamine oxidase is vital for histamine does not produce all this variety of symptoms.
dao and histamine dao deficiency
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World population affected of migraine
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Rate of people with DAO deficiency and also affected of migraine
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Estimated number of people with migraine and DAO deficiency

Origin of DAO deficiency

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Estimated number of people with fibromyalgia and DAO deficiency
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Rate of people with DAO deficiency and also affected of fibromyalgia
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Global prevalence of fibromyalgia

What is histamine?

Histamine is a molecule derived form an essential amino acid, histidine, and it is produced by decarboxylation through the L-histidine decarboxylase enzyme activity.

Histamine has many physiological and phato-physiological functions.

Know more about histamine

Histamine presence in Food

Histamine is present in many types of food and with different concentrations. It is important to take care on the diet if someone is affected of Diamino Oxidase deficiency, because the consumption of food with high concentrations of histamine can trigger many types of adverse symptoms.

Know more about histamine in food

Food which interferes in histamine metabolism

Some types of Food can generate molecules that block or inhibit the Diamino Oxidase activity.
It is important to know them and design a beneficial diet reducing and/or managing the presence of this types of food, even more if you are diagnosticated of Diamine Oxidase deficiency.

Know more about Food which interferes in histamine metabolism
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World population affected by Irritable bowel syndrome
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Estimated number of people with Irritable bowel syndrome and DAO deficiency
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Rate of people with DAO deficiency and also affected of Irritable bowel syndrome

R&D in DAO deficiency

A recopilation of Scientific articles and Research&Development works about Diamine Oxidase deficiency.

Discover the science behind dao deficiency
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Rate of people with DAO deficiency and also affected of ADHD
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World population affected by ADHD
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Estimated number of people with ADHD and DAO deficiency

Become a member of the Society is free and it allows you to get access to scientific publications on the field of DAO Deficiency, get access to the member directory of the Society and be able to get in touch with them, and also get passes for events and activities.

To become a member of any of our three committees before you must be associated in one of the member areas of the Society and subsequently send a request for admission to one of them, it will e reviewed and granted by the Board of Directors.

News

Histamine and histamine intolerance
150 150 admin

To access this content and be able to download the scientific paper in pdf you must access your member account of the Society through here.   If you are not yet a member you can register for free in one of our three areas of members: Science, Industry or Society through here.   To be…

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Evidence for a reduced histamine degradation capacity in a subgroup of patients with atopic eczema
150 150 admin

To access this content and be able to download the scientific paper in pdf you must access your member account of the Society through here.   If you are not yet a member you can register for free in one of our three areas of members: Science, Industry or Society through here.   To be…

read more
Evidence for a reduced histamine degradation capacity in a subgroup of patients with atopic eczema
150 150 admin

Evidence for a reduced histamine degradation capacity in a subgroup of patients with atopic eczema Maintz L1, Benfadal S, Allam JP, Hagemann T, Fimmers R, Novak N. 1. Department of Dermatology, University of Bonn, Germany. J Allergy Clin Immunol. 2006 May;117(5):1106-12. Epub 2006 Feb 8. PMID: 16675339 DOI: 10.1016/j.jaci.2005.11.041 Abstract BACKGROUND: A diminished histamine degradation based on a reduced diaminoxidase activity…

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The diet factor in pediatric and adolescent migraine
150 150 admin

To access this content and be able to download the scientific paper in pdf you must access your member account of the Society through here. If you are not yet a member you can register for free in one of our three areas of members: Science, Industry or Society through here.   To be a…

read more
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