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International Society of DAO Deficiency promotes the progress of science and industry in favour of the population affected by this metabolic disorder.

BECOME A MEMBER OF THE SOCIETY

Become a member of the Society is free and it allows you to get access to scientific publications on the field of DAO Deficiency, get access to the member directory of the Society and be able to get in touch with them, and also get passes for events and activities.

Be part of our commitees

To become a member of any of our three committees before you must be associated in one of the member areas of the Society and subsequently send a request for admission to one of them, it will e reviewed and granted by the Board of Directors.

The Society is composed of three Committees

Their fundamental mission is to collaborate and advice the Society`s Board of directors to ensure better delivery of its activities and work plans, allowing the generation of knowledge, innovation and health benefits.

Our Board of directors
Our General Assembly

Our committees are integrated by experts belonging to clinical, assistential and research groups, enterprises and patient associations. These represent the interaction between the worlds of science, industry and society, respectively.

know our Science commitee
know our Industry commitee
know our Social commitee

Our objectives and mission

We are focused in the improvement of quality of life of people with this enzyme deficiency.

To understand DAO deficiency’s biological basis as well as the clinical, diagnostic and therapeutic aspects and prevention more deeply.
To promote scientific developments, medical care, doctor’s office and the diagnosis of patients.
To develop and improve health care and food products. 
Objectives and Mission

Main activities in our way of development and innovation

Promote and organize campaigns

Sponsoring

Establish relations with

Know more about our Activities and events
We must be aware of the large percentage of the world’s population that is affected by adverse symptoms related to the effects of diet and with alterations in the functioning of the intestinal metabolism.
Migraine
1.050 million people affected by migraine
12%
Irritable Bowel Syndrome: 611 million people affected
7.1%
ADHD: 388 million people affected
2.1%
Fibromyalgia: 124 million people affected

What is DAO deficiency?

The decrease in the Diamine Oxidase enzime activity, which metabolize the histamine adquired from diet, triggers it absortion and acumulation in tissues and organs, producing many adverse symptons in the organism:

 

symptoms dao deficiency
Have an optimal activity of the enzyme diamine oxidase is vital for histamine does not produce all this variety of symptoms.
dao and histamine dao deficiency
KNOW MORE ABOUT DAO DEFICIENCY
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World population affected of migraine
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Rate of people with DAO deficiency and also affected of migraine
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Estimated number of people with migraine and DAO deficiency
DAO AND MIGRAINE

Origin of DAO deficiency

kNOW MORE ABOUT THE GENETIC ORIGIN OF DAO DEFICIENCY
KNOW MORE ABOUT THE PHARMACOLOGICAL ORIGIN OF DAO DEFICIENCY
KNOW MORE ABOUT THE PATHOLOGICAL ORIGIN OF DAO DEFICIENCY
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Estimated number of people with fibromyalgia and DAO deficiency
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Rate of people with DAO deficiency and also affected of fibromyalgia
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Global prevalence of fibromyalgia
DAO AND FIBROMYALGIA

What is histamine?

Histamine is a molecule derived form an essential amino acid, histidine, and it is produced by decarboxylation through the L-histidine decarboxylase enzyme activity.

Histamine has many physiological and phato-physiological functions.

Know more about histamine

Histamine presence in Food

Histamine is present in many types of food and with different concentrations. It is important to take care on the diet if someone is affected of Diamino Oxidase deficiency, because the consumption of food with high concentrations of histamine can trigger many types of adverse symptoms.

Know more about histamine in food

Food which interferes in histamine metabolism

Some types of Food can generate molecules that block or inhibit the Diamino Oxidase activity.
It is important to know them and design a beneficial diet reducing and/or managing the presence of this types of food, even more if you are diagnosticated of Diamine Oxidase deficiency.

Know more about Food which interferes in histamine metabolism
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World population affected by Irritable bowel syndrome
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Estimated number of people with Irritable bowel syndrome and DAO deficiency
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Rate of people with DAO deficiency and also affected of Irritable bowel syndrome
DAO AND IBS

R&D in DAO deficiency

A recopilation of Scientific articles and Research&Development works about Diamine Oxidase deficiency.

Discover the science behind dao deficiency
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Rate of people with DAO deficiency and also affected of ADHD
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World population affected by ADHD
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Estimated number of people with ADHD and DAO deficiency
DAO AND ADHD
BECOME A MEMBER OF THE SOCIETY

Become a member of the Society is free and it allows you to get access to scientific publications on the field of DAO Deficiency, get access to the member directory of the Society and be able to get in touch with them, and also get passes for events and activities.

Be part of our commitees

To become a member of any of our three committees before you must be associated in one of the member areas of the Society and subsequently send a request for admission to one of them, it will e reviewed and granted by the Board of Directors.

News

Serum Diamine Oxidase Values, Indicating Histamine Intolerance, Influence Lactose Tolerance Breath Test Results
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Download the paper clicking here Abstract: Lactose intolerance (LIT) is one of the major causes of irritable bowel syndrome (IBS) spectrum complaints. Differences in inadequate lactose digestion are described as various LIT phenotypes with basically unknown pathophysiology. In LIT patients, we retrospectively assessed the effect of histamine intolerance (HIT) on expiratory hydrogen (H2) during H2…

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Intestinal Dysbiosis in Patients with Histamine Intolerance
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New study published about microbiota, histamine intolerance and DAO deficiency by the research team of the University of Barcelona (Dr. Mª Carmen Vidal). Adding clinical and scientific evidence every day. Download the paper through here Abstract: An underlying cause of histamine intolerance is diamine oxidase (DAO) deficiency, which leads to defective homeostasis and a higher systemic…

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International Congress of DAO Deficiency’21
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YOU ARE INVITED TO MAP A NEW FUTURE IN MANAGING DAO DEFICIENCY Attending the International Congress of DAO Deficiency`21 From the International Society of DAO Deficiency we are delighted to invite you to the International Congress of DAO Deficiency`21, to be held 4 November 2021, in virtual format.  Our end goal: is to reinforce knowledge of DAO Deficiency…

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Associations Between Migraine, Celiac Disease, Non-Celiac Gluten Sensitivity and Activity of Diamine Oxidase
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Associations Between Migraine, Celiac Disease, Non-Celiac Gluten Sensitivity and Activity of Diamine Oxidase Download pdf K Griauzdaitė1, K Maselis2, A Žvirblienė1, A Vaitkus1, D Jančiauskas1, I Banaitytė-Baleišienė1, L Kupčinskas1, D Rastenytė1 Medical Hypotheses Volume 142, September 2020, 109738 https://doi.org/10.1016/j.mehy.2020.109738 Abstract Background and pilot study: Recent reports reveal a close relationship between migraine and gastrointestinal disorders (GI), such as celiac disease (CD) and non-celiac gluten sensitivity…

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