{"id":9087,"date":"2013-10-01T11:38:55","date_gmt":"2013-10-01T11:38:55","guid":{"rendered":"https:\/\/www.deficitdao.org\/?p=9087"},"modified":"2019-01-25T10:10:44","modified_gmt":"2019-01-25T10:10:44","slug":"migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013","status":"publish","type":"post","link":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/","title":{"rendered":"Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013"},"content":{"rendered":"<p><strong>VIENNA, Austria \u2014 Preventive treatment with diamine oxidase (DAO), an enzyme that degrades histamine, significantly shortened the duration of migraine attacks and trended toward reducing the number of episodes.<\/strong><\/p>\n<p>Histamine is present in many foods, is released in allergic reactions, and is one of the chemical mediators that contributes to migraine. About 25% of the population may have an alteration in DAO that decreases its activity in breaking down histamine. The enzyme is expressed most in the intestine, kidney, and placenta.<\/p>\n<blockquote><p>&#8220;We diagnosed 137 patients who have a migraine, of whom 119 showed deficits of the activity of the enzyme, around 87% of the total patients that we have studied,&#8221; said Joan Izquierdo, MD, from the Faculty of Health Sciences at the International University of Catalonia and the neurology service at Catalonia General Hospital in Barcelona, Spain.<\/p><\/blockquote>\n<p>He said normal enzyme activity is a score of at least 80 histamine-degrading units [HDU]\/mL. Read more&#8230;<\/p>\n<h5><strong><a href=\"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2018\/12\/Migraine_Attacks_Shortened_by_Diamine_Oxidase_Supplements.pdf\">Download pdf<\/a><\/strong><\/h5>\n","protected":false},"excerpt":{"rendered":"<p>VIENNA, Austria \u2014 Preventive treatment with diamine oxidase (DAO), an enzyme that degrades histamine, significantly shortened the duration of migraine attacks and trended toward reducing the number of episodes. Histamine [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":9092,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[122,127],"tags":[],"class_list":["post-9087","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-publications-in-the-media"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013\" \/>\n<meta property=\"og:description\" content=\"VIENNA, Austria \u2014 Preventive treatment with diamine oxidase (DAO), an enzyme that degrades histamine, significantly shortened the duration of migraine attacks and trended toward reducing the number of episodes. Histamine [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/\" \/>\n<meta property=\"og:site_name\" content=\"deficitdao.org\" \/>\n<meta property=\"article:published_time\" content=\"2013-10-01T11:38:55+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2019-01-25T10:10:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2013\/10\/medscape-20-aniversay.png\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"360\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/\",\"url\":\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/\",\"name\":\"Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013\",\"isPartOf\":{\"@id\":\"https:\/\/www.deficitdao.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2013\/10\/medscape-20-aniversay.png\",\"datePublished\":\"2013-10-01T11:38:55+00:00\",\"dateModified\":\"2019-01-25T10:10:44+00:00\",\"author\":{\"@id\":\"https:\/\/www.deficitdao.org\/#\/schema\/person\/b5af2351e8032fefd080ea4c700a748b\"},\"breadcrumb\":{\"@id\":\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#primaryimage\",\"url\":\"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2013\/10\/medscape-20-aniversay.png\",\"contentUrl\":\"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2013\/10\/medscape-20-aniversay.png\",\"width\":640,\"height\":360},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\/\/www.deficitdao.org\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.deficitdao.org\/#website\",\"url\":\"https:\/\/www.deficitdao.org\/\",\"name\":\"deficitdao.org\",\"description\":\"International Society of DAO deficiency: biomedical R&amp;D in diamine oxidase deficiency and diet histamine induced disorders\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.deficitdao.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.deficitdao.org\/#\/schema\/person\/b5af2351e8032fefd080ea4c700a748b\",\"name\":\"admin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.deficitdao.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c83c593ca82101eb47019b6652e1af17b97e7ed8a7cff74716702d46aedf4c10?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c83c593ca82101eb47019b6652e1af17b97e7ed8a7cff74716702d46aedf4c10?s=96&d=mm&r=g\",\"caption\":\"admin\"},\"url\":\"https:\/\/www.deficitdao.org\/en\/author\/admin\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/","og_locale":"en_US","og_type":"article","og_title":"Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013","og_description":"VIENNA, Austria \u2014 Preventive treatment with diamine oxidase (DAO), an enzyme that degrades histamine, significantly shortened the duration of migraine attacks and trended toward reducing the number of episodes. Histamine [&hellip;]","og_url":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/","og_site_name":"deficitdao.org","article_published_time":"2013-10-01T11:38:55+00:00","article_modified_time":"2019-01-25T10:10:44+00:00","og_image":[{"width":640,"height":360,"url":"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2013\/10\/medscape-20-aniversay.png","type":"image\/png"}],"author":"admin","twitter_card":"summary_large_image","twitter_misc":{"Written by":"admin","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/","url":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/","name":"Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013","isPartOf":{"@id":"https:\/\/www.deficitdao.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#primaryimage"},"image":{"@id":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#primaryimage"},"thumbnailUrl":"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2013\/10\/medscape-20-aniversay.png","datePublished":"2013-10-01T11:38:55+00:00","dateModified":"2019-01-25T10:10:44+00:00","author":{"@id":"https:\/\/www.deficitdao.org\/#\/schema\/person\/b5af2351e8032fefd080ea4c700a748b"},"breadcrumb":{"@id":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#primaryimage","url":"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2013\/10\/medscape-20-aniversay.png","contentUrl":"https:\/\/www.deficitdao.org\/wp-content\/uploads\/2013\/10\/medscape-20-aniversay.png","width":640,"height":360},{"@type":"BreadcrumbList","@id":"https:\/\/www.deficitdao.org\/en\/2013\/10\/01\/migraine-attacks-shortened-by-diamine-oxidase-supplements-publicated-in-medscape-by-daniel-m-keller-phd-oct-01-2013\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/www.deficitdao.org\/en\/"},{"@type":"ListItem","position":2,"name":"Migraine Attacks Shortened by Diamine Oxidase Supplements. Published in medscape by Daniel M. Keller, PhD, Oct 01 2013"}]},{"@type":"WebSite","@id":"https:\/\/www.deficitdao.org\/#website","url":"https:\/\/www.deficitdao.org\/","name":"deficitdao.org","description":"International Society of DAO deficiency: biomedical R&amp;D in diamine oxidase deficiency and diet histamine induced disorders","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.deficitdao.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.deficitdao.org\/#\/schema\/person\/b5af2351e8032fefd080ea4c700a748b","name":"admin","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.deficitdao.org\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c83c593ca82101eb47019b6652e1af17b97e7ed8a7cff74716702d46aedf4c10?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c83c593ca82101eb47019b6652e1af17b97e7ed8a7cff74716702d46aedf4c10?s=96&d=mm&r=g","caption":"admin"},"url":"https:\/\/www.deficitdao.org\/en\/author\/admin\/"}]}},"_links":{"self":[{"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/posts\/9087","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/comments?post=9087"}],"version-history":[{"count":6,"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/posts\/9087\/revisions"}],"predecessor-version":[{"id":9744,"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/posts\/9087\/revisions\/9744"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/media\/9092"}],"wp:attachment":[{"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/media?parent=9087"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/categories?post=9087"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.deficitdao.org\/en\/wp-json\/wp\/v2\/tags?post=9087"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}