{"id":6476,"date":"2018-11-28T12:04:24","date_gmt":"2018-11-28T12:04:24","guid":{"rendered":"https:\/\/www.deficitdao.org\/?page_id=6476"},"modified":"2019-01-22T15:05:42","modified_gmt":"2019-01-22T15:05:42","slug":"projects","status":"publish","type":"page","link":"https:\/\/www.deficitdao.org\/en\/projects\/","title":{"rendered":"Projects"},"content":{"rendered":"

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Projects<\/span><\/h1>[\/vc_column][vc_column width=”1\/2″]
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Clinical trials and research projects on DAO Deficiency:<\/span><\/h2>[\/vc_column_inner][\/vc_row_inner][vc_row_inner css=”.vc_custom_1547575733977{margin-right: 20px !important;margin-bottom: 50px !important;padding-top: 30px !important;padding-right: 30px !important;padding-bottom: 30px !important;padding-left: 30px !important;background-image: url(https:\/\/www.deficitdao.org\/wp-content\/uploads\/2018\/12\/blanco-al-61.png?id=8864) !important;border-radius: 20px !important;}”][vc_column_inner]

2018-2019<\/p><\/blockquote>

Effect to Gastrointestinal Barrier Function During Laparoscopic Gastrectomy With Deep vs Moderate Neuromuscular Blockade.<\/span><\/h3>[vc_column_text]Link to the Clinical Trial page in NIH ClinicalTrials.gov<\/a><\/strong><\/p>\n

Sponsor: The First Affiliated Hospital with Nanjing Medical University<\/strong>
\nCollaborator: Wu Jieping Medical Foundation<\/strong>
\nInformation provided by (Responsible Party): The First Affiliated Hospital with Nanjing Medical University<\/strong><\/p>\n

Brief Summary:<\/h3>\n
On the basis of moderate pneumoperitoneum pressure(10 mmHg), this study evaluates the effect of different level of neuromuscular blockade to gastrointestinal barrier function during laparoscopic gastrectomy. 60 patients are randomized to 2 arms ,The patients in deep NMB\uff08PTC=1-2\uff09will receive high dose rocuronium ;While the patients in moderate NMB\uff08TOF=1-2\uff09will receive moderate dose rocuronium.<\/div>\n

<\/h3>\n

Detailed Description:<\/h3>\n
Different level of neuromuscular blockade can affect the demand of pneumoperitoneum pressure,while high level of pneumoperitoneum pressure may cause some damage to gastrointestinal barrier which is important to the recovery of the patient. In this study,we will evaluate the effect of different level of neuromuscular blockade to the barrier by DAO and D-lactic in plasma, the microstructural changes of intestinal tract will be observed under scanning electron microscope and the recovery of intestinal function will be recorded.<\/div>\n

<\/h3>\n

Study design:<\/h3>\n
\n\n\n\n\n\n\n\n\n\n\n\n\n
Study Type<\/span>:<\/td>\nInterventional \u00a0(Clinical Trial)<\/td>\n<\/tr>\n
Estimated\u00a0Enrollment<\/span>:<\/td>\n60 participants<\/td>\n<\/tr>\n
Allocation:<\/td>\nRandomized<\/td>\n<\/tr>\n
Intervention Model:<\/td>\nParallel Assignment<\/td>\n<\/tr>\n
Masking:<\/td>\nNone (Open Label)<\/td>\n<\/tr>\n
Primary Purpose:<\/td>\nTreatment<\/td>\n<\/tr>\n
Official Title:<\/td>\nEffect to Gastrointestinal Barrier Function During Laparoscopic Gastrectomy With Deep vs Moderate Neuromuscular Blockade.<\/td>\n<\/tr>\n
Estimated\u00a0Study Start Date<\/span>:<\/td>\nJanuary 1, 2019<\/td>\n<\/tr>\n
Estimated\u00a0Primary Completion Date<\/span>:<\/td>\nDecember 31, 2019<\/td>\n<\/tr>\n
Estimated\u00a0Study Completion Date<\/span>:<\/td>\nDecember 31, 2019<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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2017-2019<\/p><\/blockquote>

DIAMINE-OXIDASE (DAO) TREATMENT ON PATIENTS WITH NON-ALLERGIC RHINITIS: A RANDOMIZED, CONTROLLED, DOUBLE-BLIND CLINICAL TRIAL TO ENSURE SAFETY AND EFFICACY.<\/span><\/h3>[vc_column_text]1.Mayo1<\/sup>, GN. Esqu\u00eda1<\/sup>, MJ. Rial2<\/sup><\/em><\/p>\n

1<\/sup><\/em>Otorhinolaryngology Department.<\/em><\/p>\n

2<\/sup><\/em>Allergology Department.<\/em><\/p>\n

Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC).<\/em><\/p>\n

Project co-sponsored by DR Healthcare<\/em>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner css=”.vc_custom_1545905739667{margin-right: 10px !important;margin-bottom: 50px !important;padding-top: 30px !important;padding-right: 30px !important;padding-bottom: 30px !important;padding-left: 30px !important;background-image: url(https:\/\/www.deficitdao.org\/wp-content\/uploads\/2018\/12\/blanco-al-61.png?id=8864) !important;border-radius: 20px !important;}”][vc_column_inner]

2016-2019<\/p><\/blockquote>

OBTAINING PROBIOTIC MICROORGANISMS WITH ENDOGENOUS DAO ACTIVITY.<\/span><\/h3>[vc_column_text]M.Carmen Vidal Carou, Mariluz latorre, Teresa Veciana, Oriol Comas.<\/em><\/p>\n

Universidad de Barcelona<\/em><\/p>\n

Project co-sponsored by DR Healthcare, included in the Ris3Cat Food Community (Ris3Cat is an organization of the Catalan Government designed to promote R&D projects)<\/em><\/p>\n

Project co-funded by the European Union through the European Regional Development Fund<\/em>[\/vc_column_text]

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Scientific Publications in DAO Deficiency<\/span><\/a><\/div>
Apply for membership to the Scientific area<\/span><\/a><\/div>[\/vc_column][vc_column width=”1\/3″ css=”.vc_custom_1545905618480{padding-top: 30px !important;padding-right: 30px !important;padding-bottom: 30px !important;padding-left: 30px !important;background-image: url(https:\/\/www.deficitdao.org\/wp-content\/uploads\/2018\/11\/1.2-degradado-fondo-sec-1-1920×500.png?id=5058) !important;background-position: 0 0 !important;background-repeat: no-repeat !important;border-radius: 20px !important;}”][vc_widget_sidebar sidebar_id=”grve-default-sidebar”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

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[…]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-6476","page","type-page","status-publish","hentry"],"yoast_head":"\nProjects<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.deficitdao.org\/en\/projects\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Projects\" \/>\n<meta property=\"og:description\" content=\"[vc_row heading_color=”light” bg_type=”hosted_video” bg_video_type=”normal” bg_video_device=”yes” header_feature=”yes” padding_top=”150″ padding_bottom=”150″ bg_video_mp4=”https:\/\/www.deficitdao.org\/wp-content\/uploads\/2018\/11\/Abstract-5265-2.mp4″][vc_column width=”1\/2″][\/vc_column][vc_column 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